Does Big Pharma Care How You Stop Smoking?

Wednesday, July 8, 2009 by John Bancroft

Federal regulators have ordered new safety language about quitting smoking on the smoking cessation drugs Chantix (varenicline) and Zyban (buproprion). The two stop smoking meds are getting the toughest warning added to their labels, alerting doctors and patients to potentially severe mental health risks when using these drug to quit smoking , including behavioral changes, depression, hostility, suicide, and suicidal thoughts, as well as warnings about allergic and skin reactions.
The FDA has been reviewing Chantix safety since 2007, after hundreds of reports of erratic, aggressive and suicidal behavior when using it as part of a smoking cessation program. But as the agency notes, it's difficult to confirm these drugs are directly responsible, because nicotine withdrawal itself can be very difficult to endure. There's also the possibility that when Chantix is used to stop smoking it exacerbates symptoms of underlying mental illness rather than causing them--a problem that would have gone undetected in clinical trials because they excluded patients with a history of mental illness.
Hence the new trials FDA is requiring both Pfizer and GlaxoSmithKline, Zyban's maker, to undertake. Pfizer says it's currently conducting a safety study involving patients with schizophrenia and is in talks with the FDA regarding comparative studies. Glaxo will also be required to study Zyban's mental health effects on patients, including those with pre-existing mental problems.
"The risk of serious adverse events while taking these smoking cessation/stop smoking products must be weighed against the significant health benefits of quitting smoking," said Janet Woodcock, M.D., director, the FDA's Center for Drug Evaluation and Research. "Smoking is the leading cause of preventable disease, disability, and death in the United States and we know these products are effective aids in helping people break their addiction to nicotine.
Pfizer won't yet say how the warning might affect its financial forecast or its Chantix sales force, but promises an update July 22 on sales figures for its primary care unit, in tandem with its earnings report. Meanwhile, GSK hasn't released a statement at all, despite the fact that the warning goes onto two of its meds: Zyban is sold as an antidepressant under the brand name Wellbutrin, and that drug gets updated "boxed warning" language added to its current "boxed warning" of suicidal thoughts and behavior. Generic versions, too. But Glaxo doesn't make much off Zyban, while Chantix is one of Pfizer's top selling meds, bringing in $846 million last year.

These products may not be the best stop smoking aids as alternatives to smoking and nicotine addiction. It may be preferable to seek other tips on quitting smoking with less potential for severe adversities.

Some Tips on Best Stop Smoking Aids

Thursday, June 18, 2009 by John Bancroft
Qutting smoking isn't easy. It's nicotine addiction and like any other addiction it requires help. Here's a few tip on quitting smoking:
1.When you try to stop smoking make sure you're ready.
2.Make sure you have your stop smoking "quit smoking day" in your own hands.
3.Don't let yourself be"told" to quit smoking  for any other reason but your own.
4.Have some tools on hand to get you through those times when you want to smoke and have those "cravings".

There are natural products like smokerZchoice that help with cravings and irritabilty.

BUT remember to stick with it. Your odds of becoming a permanent non smoker go up everytime you try. "

Only 1% or 2% of all smokers that try to quit smoking are successful long term

Saturday, June 6, 2009 by John Bancroft
 
When is come to stopping smoking you can be sure that quitting using tobacco is no easy task.

Your brain has become sensitized to nicotine and your body has been habituated to your smoking habit. Until you are firm in your resolve to quit smoking it is better to reduce the amount of cigarettes you smoke and cut down one or two cigarettes a day. Quit smoking cold? That is not a good tip on quitting smoking. If you are not ready to stop smoking there is a high likelihood that you will not be successful and fall prey to good old nicotine withdrawal.

In the meantime simple 5% reduction in the amount of cigarettes you smoke can reduce the harm. So next time you want to reach for a smoke reach for a smoking alternative instead.

And when you are ready to make the choice your chances for success will be greater.